University Pierre and Marie Curie (UPMC), France, The METIS lab, in association with the Center of National Research (CNRS), is focusing its activity on hydrogeophysical and biogeochemical modelling including ecological modelling experimentally-based approach (Riverstrahler), taking explicitly the processes of microorganisms involved in the C, N, P, Si and oxygen cycles. The model links the water quality of river continuums from land-to-sea with human activities in the basin (water pollution by domestic effluents, agriculture contaminations). The nitrogen cascade and the nitrogen cycle in the water-agri-food have received major attention in the last 5 years, from local to global scales. The interest of the group includes analysis of the performance of organic agriculture in terms of N losses in the environment. Leads the West Europe regional demonstration activity.